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Safeguard Scientifics to Announce First Quarter 2010 Financial Results on Thursday, May 6th

Conference Call and Webcast Scheduled for 9:00am ET  

Wayne, PA, April 22, 2010 – Safeguard Scientifics, Inc. (NYSE: SFE), a holding company that builds value in growth-stage life sciences and technology companies, today announced that it will release its financial results for the first quarter ended March 31, 2010 prior to market open on Thursday, May 6, 2010.

SAFEGUARD SCIENTIFICS FIRST QUARTER 2010 CONFERENCE CALL
Please call at least 10 minutes prior to the call to register. 

Date: Thursday, May 6, 2010 

Time: 9:00am ET 

Webcast: www.safeguard.com/earnings 

Conference ID#:
70361890 

Call-in Number: 877-640-9871 
(International) +914-495-8549 

Replay Number:
800-642-1687
(International) +706-645-9291
Replay available through June 4, 2010 at 11:59 pm ET 

Podcast:www.safeguard.com/podcast
Available approximately 24 hours after the conclusion of the earnings call 

Speakers: President and CEO Peter J. Boni; Senior Vice President and CFO Stephen T. Zarrilli

Format:
Discussion of first quarter 2010 financial results followed by Q&A.

For more information please contact IR@safeguard.com.

About Safeguard Scientifics
Founded in 1953 and based in Wayne, PA, Safeguard Scientifics, Inc. (NYSE: SFE) provides growth capital for entrepreneurial and innovative life sciences and technology companies. Safeguard targets life sciences companies in Molecular and Point-of-Care Diagnostics, Medical Devices, Regenerative Medicine and Specialty Pharmaceuticals, and technology companies in Internet / New Media, Financial Services IT and Healthcare IT with capital requirements of up to $25 million. Safeguard participates in expansion financings, corporate spin-outs, management buyouts, recapitalizations, industry consolidations and early-stage financings. For more information, please visit our website at www.safeguard.com or our blog at blog.safeguard.com.

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